Critical role of cytosolic phospholipase A2 in bronchial mucus hypersecretion in CFTR-deficient mice
نویسندگان
چکیده
منابع مشابه
Critical role of cytosolic phospholipase A2{alpha} in bronchial mucus hypersecretion in CFTR-deficient mice.
Cystic fibrosis (CF) is due to mutations in the CF transmembrane conductance regulator gene CFTR. CF is characterised by mucus dehydration, chronic bacterial infection and inflammation, and increased levels of cytosolic phospholipase A2α (cPLA2α) products in airways. We aimed to examine the role of cPLA2α in the modulation of mucus production and inflammation in CFTR-deficient mice and epitheli...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2010
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00183409